Tag Archives: cytotoxicity

Environmental Health Perspectives, September 2014: “Acrolein-Exposed Normal Human Lung Fibroblasts in Vitro: Cellular Senescence, Enhanced Telomere Erosion, and Degradation of Werner’s Syndrome Protein”

From: http://ehp.niehs.nih.gov/1306911/ Environmental Health Perspectives, Volume 122, Issue 9, September 2014 Jun-Ho Jang, Shannon Bruse, Salam Huneidi, Ronald M. Schrader, Martha M. Monick, Yong Lin, A. Brent Carter,Aloysius J. Klingelhutz, and Toru Nyunoya Acrolein-Exposed Normal Human Lung Fibroblasts in Vitro: Cellular Senescence, Enhanced Telomere Erosion, and Degradation of … Continue reading

Posted in Acrolein and Respiratory Health, Acrolein and Telomere Erosion, Acrolein and WRN Protein Instability, Acrolein Health Risks | Tagged , , , , , , , , , , | Leave a comment

Diesel Exhaust Particles Selectively Induce both Proinflammatory Cytokines and Mucin Production in Cornea and Conjunctiva Human Cell Lines

From: http://www.ncbi.nlm.nih.gov/pubmed/23722391 PubMed.gov Invest Ophthalmol Vis Sci. 2013 Jul 16;54(7):4759-65. doi: 10.1167/iovs.12-10541. Tau J, Novaes P, Matsuda M, Tasat DR, Saldiva PH, Berra A. Diesel exhaust particles selectively induce both proinflammatory cytokines and mucin production in cornea and conjunctiva human cell lines The authors state that the objective … Continue reading

Posted in Air Pollution and Eyes | Tagged , , , , , , | Leave a comment

Acrolein Induces Alzheimer’s Disease-like Pathologies in Vitro and in Vivo.

From: http://www.ncbi.nlm.nih.gov/pubmed/23296102 Toxicol Lett. 2013 Jan 4;217(3):184-191. doi: 10.1016/j.toxlet.2012.12.023. [Epub ahead of print] Huang YJ, Jin MH, Pi RB, Zhang JJ, Ouyang Y, Chao XJ, Chen MH, Liu PQ, Yu JC, Ramassamy C, Dou J, Chen XH, Jiang YM, Qin J. Acrolein induces Alzheimer’s disease-like pathologies in vitro and in vivo. According to the authors, … Continue reading

Posted in Acrolein and Alzheimer's Disease | Tagged , , , , | 1 Comment