Exposure to Severe Urban Air Pollution Influences Cognitive Outcomes, Brain Volume, and Systemic Inflammation in Clinically Healthy Children

From: http://www.ncbi.nlm.nih.gov/pubmed/22032805

Brain Cogn. 2011 Dec;77(3):345-55. Epub 2011 Oct 26.

Exposure to severe urban air pollution influences cognitive outcomes, brain volume, and systemic inflammation in clinically healthy children

Calderón-Garcidueñas L, Engle R, Mora-Tiscareño A, Styner M, Gómez-Garza G, Zhu H, Jewells V, Torres-Jardón R, Romero L, Monroy-Acosta ME, Bryant C, González-González LO, Medina-Cortina H, D’Angiulli A.

The authors state: “Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children.”

In this study, the authors “tested whether patterns of brain growth, cognitive deficits, and white matter hyperintensities (WMH) are associated with exposures to severe air pollution.”

The authors conclude, “These findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.”

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